I just used Pogoplug to access my drives remotely. I found a PDF file I wanted to send, I hit the transfer icon (lower right corner of pogoplug for iphone) and had options to open in some application (which I did). I opened it in pdfreader pro (an excellent iPhone app by the way).

It ended up in the "inbox" of pdfreader, from there I just sent it by email to another account I have, and voila, it was there.

So I accessed a JPG using Pogoplug, it appears in the pogoplug app, then used the same idea to transfer it, this time I had a different set of options, including putting the jpg in my "camera roll" which is another place on the iPhone that can be used to send photos. It works like a charm.

PDF Reader Pro can get files using several methods, including local WiFi access (turn on WiFi access, and go to the PDF Reader app by going to a local IP address and port number that it displays for you on the screen)

You can grab things using it's "browser download" - From google, I searched for a manual on an item I own, it shows me the PDF link, I select it, wait until it downloads, look at it, then decide to save the "page" (or several pages actually.

This time, instead of being in my "inbox" directory in PDF Reader Pro where the pogoplug PDF file went, this time it's in the "downloads" folder inside PDF Reader Pro. I open the file, and look at the options I have which are:

1. Text Reflow
2. Text Search
3. Air Print
4. Auto Flow
5. Lock Horizontal
6. Lock Rotation
7. Jump to page
8. E-mail out
9. About this file

The about feature tells me the PDF file is version 1.a, pages 12, creator Adobe InDesign CS3, Creatoin date: 2010-07-07 09:50:19

It also shows the various limitations of the PDF file, in this case "Allow Copying: No"

I just took a WORD doc file, put it on my pogoplug drive from my computer.

Then I accessed it with the iPhone using pogoplug. It downloaded and it was viewable. Then I did the transfer icon thing and sent it to the same PDF Reader Pro, and it allowed me to see it, no problem, as a DOC file.

I saw that I could convert it to PDF inside my iPhone, but had to move the file (easy) to another directory first. So I used the features in the PDF Reader Program to grab the file and deposit it in a "private" folder, then converted it to PDF, and I now have the DOC file version and the more ubiquitous format, the PDF version, and I can send EITHER one by E-mail.

I have both the iPhone and an iPad, so bought PDF Reader Pro for each one. In total, it was about $15, and well worth it in my opinion.

Spreadsheets (XLS) files can be grabbed using pogoplug, and sent to PDF REader Pro, and inspected, and converted to PDF format after moving the file out of the inbox.

Now, you can investigate Spreadsheet specific programs, just type "spreadsheet" in the search on the iTunes store, there are too many to test, but some look very interesting for getting managing, creating, and mailing spreadsheets.

What's nice about PDF Reader Pro is that it is one of the "known" places that Pogoplug for the iPhone (and ipad) can transfer files to, so it's painless to move things into PDF Reader Pro if they originate on a pogoplug drive.

Hope this helps. Bottom line, I think the answer to your question is "Yes" -- a long explanation as to why I think Yes is the right answer. I hope it works for you.

Jeff