I get an error pretty often when I try to delete a file using either the finder or commandline when I try to delete a file that is over say 6-700mb (avg 900mb) files.  I get the following error: rm: Name_Of_File.mp4: Socket is not connected

After this error comes up I can't access the drive through Mac drive app without rebooting my mac.

Any ideas?  I'm guessing it's a mac fuse problem, but any incite would be great.  I have a Drobo with 4 2tb drives attached.  Formatted as HFS+  I have MacFues 2.1.5 beta installed (latest).  It has been more stable with copies/deletes through the Mac Drive app than it used to be, but I still get this problem pretty often.

Any help would be greatly appreciated.